Blood pressure and NxStage

system · July 18, 2006, 6:31pm

Did you find that your bp was higher on NxStage?

Gus · July 19, 2006, 1:07am

:roll: /// :?

one of the most noticeable improvements doing short-daily is normalized blood pressure, took me 3 months for it to normalize…

ADIOS HIGH BLOOD PRESSURE MEDS!

Headbandgrrl · July 19, 2006, 1:28am

Has anyone read the journal articles on lactate hemodialysis solutions causing a greater occurance of hypotension than bicarbonate based solutions?

I am very interested in this because I have hypotension, and I have a sneaky suspicion that the rock bottom pressures I have recently reached are either because my bicarb levels are too low (though my labs are borderline/ok), or there is something else going on.

Heather, to answer your question regarding NxStage- for me, my blood pressure was already low, seems to be even lower since switching modailities. Whether or not NxStage had anything to do with that…I don’t know, yet.

Gus · July 19, 2006, 1:42am

Headbandgrrl:

Has anyone read the journal articles on lactate hemodialysis solutions causing a greater occurance of hypotension than bicarbonate based solutions?

Never read that, where’s this journal at?

I am very interested in this because I have hypotension, and I have a sneaky suspicion that the rock bottom pressures I have recently reached are either because my bicarb levels are too low (though my labs are borderline/ok), or there is something else going on.

Heather, to answer your question regarding NxStage- for me, my blood pressure was already low, seems to be even lower since switching modailities. Whether or not NxStage had anything to do with that…I don’t know, yet.

[b]I think it has to do with the more frequent dialysis, and I did see those occurences in some people using High-Flux dialyzers namely the F80 in-center on 3x week…now that your doing daily-short your getting alot more off and that’s one reason its dropping more, but you’d have to increase sodium in your diet…whats the lowest your pressure has dropped? No cramping?

The lowest mine has gone is 65/55 with 90 pulse rate…I manage to bring it back up by increasing sodium in my diet and by not taking too much fluid off…[/b]

Before doing daily-short you were in-center doing 3x a week? And you had hypotension in-center?

Headbandgrrl · July 19, 2006, 2:30am

Gus! I just wrote a really long response to this and I lost it somehow. I need to get to sleep as it is 3am here. But…Quickly…

1.) I did a google search for “bicarbonate, dialysis, and hypotension.” The articles were on the first two pages.

2.) If I eat anymore sodium, I am going to burst!! hehe. Salt, strong coffee, anger…none of it works. Nope, I don’t cramp. My pulse varies from 86-130. No pattern there either.

My bp has been lowish since re-starting incenter in 2001, but it did continue to decrease during short daily (fresenius 2008K full size) from 3/04-10/05, but it leveled out during Nocturnal during 10/04-11/05, and stayed normal except for a few instances of sepsis due to my RO not carbon tanks not being changed adequately. (Long story). I had a second transplant in Nov 2005, unfortunately the transplant didn’t work and I ended up in-center from 11/2005-2/2006, but I was fighting an infection in the failed transplant incision so my bp dropped, then rose back to normal toward February. Since February 2006, my bp has been progressively lowering to the lowest levels…60/40, 80/59.

It doesn’t matter if I have 5 kg or .5 kg over my dry weight, either.

My bp seems to be erratic which led me to believe I have a bicarb issue. I have had so many other secondary issues that I am now trying to systemically figure this out. But I have noticed a significant difference during my NxStage treatments.

Side note: Quite frankly, if it wasn’t for water issues at my apartment, I would still be on Nocturnal. I felt the best during those treatments. But I do LOVE the portability of NxStage!!

Gus:

[quote=Headbandgrrl]Has anyone read the journal articles on lactate hemodialysis solutions causing a greater occurance of hypotension than bicarbonate based solutions?

Never read that, where’s this journal at?

I am very interested in this because I have hypotension, and I have a sneaky suspicion that the rock bottom pressures I have recently reached are either because my bicarb levels are too low (though my labs are borderline/ok), or there is something else going on.

Heather, to answer your question regarding NxStage- for me, my blood pressure was already low, seems to be even lower since switching modailities. Whether or not NxStage had anything to do with that…I don’t know, yet.

[b]I think it has to do with the more frequent dialysis, and I did see those occurences in some people using High-Flux dialyzers namely the F80 in-center on 3x week…now that your doing daily-short your getting alot more off and that’s one reason its dropping more, but you’d have to increase sodium in your diet…whats the lowest your pressure has dropped? No cramping?

[/quote]

Beth_Witten_MSW_ACSW · July 19, 2006, 8:16am

Here’s information from the National Kidney Foundation’s K/DOQI clinical practice guidelines for cardiovascular disease that discuss hypotension during dialysis (intradialytic hypotension). The guideline discusses what conditions contribute to it.

http://www.kidney.org/Professionals/kdoqi/guidelines_cvd/intradialytic.htm