Judith Bernardini says, "First of all, I would like to say that PD is not to be painful, so we must address this problem right away. You have been told correctly that the tip of the catheter is clearly pressing on a nerve or several nerves perhaps. Drain pain is caused when the catheter no longer floats in abdominal cavity, and then pushes against organs, nerves, bowel, etc. I presume you do not have pain when you are full. When you are on CAPD, you can manually slow the drain of fluid and stop it altogether when pain begins. What you need to do is determine how much fluid remains in your abdomen when the pain begins. And at that point you should stop draining. You will know how much you put in for that exchange and how much you generally drain. And how far you are from a complete drain. On the cycler, you can program the machine to stop draining at a certain point and begin filling again. Since you are new to PD, you probably have a lot of residual renal function (that is, you still pee a fair amount), so having full fills and drains are not as important as might be for someone who relies totally on dialysis for their clearance of fluids and solutes (creatinine, urea, phosphorus, etc). Your PD nurse can help you determine how much PD you need. It is possible you need an xray of your abdomen to determine where the tip of the catheter lies. And you should consider replacing the catheter, getting a shorter catheter which should solve the problem. Waiting for a kidney transplant can be quite a long wait so try to get your PD nurse and nephrologist to make life better now. Best of luck."
I would add that some folks have had success with raising or lowering the cycler relative to their heads--often just by a few inches, but sometimes even by as much as a foot.