Beth, if that’s as uncommon as you think it is, it is no wonder my doctor and the PD dialysis nurses seem to turn a deaf ear to my complaints of dialysis causing twitches. At first they were few and far between, but then so were my first PD treatments, two or three days a week at the dialtsis clinic. Then I got home dialtsis, slowly the twiching progress. All this time the doctor and nurses were telling me it’s the toxins in my body. At first I believed that as I had no reason to doubt as they were the professionals. However I didn’t do the dialysis as frequently as they wanted and insead of every night for 8 hours, ( I couldn’t sleep through the drain pain), I would do it every second day for four hours, it’s seemed to be working for me, my toxin levels were slowly going down I felt pretty good for about two days, the I started twiching and thought uh-oh my toxin levels must be going up, so I would do another dialsis session. I seemed fine until I laid down, and this uncontrolable twiching began, further blood testing show my toxin levels dropping further, in all fairness some were still high. Although toxin levels were dropping the twiching worsened. The doctor made mention my toxin levels were going down on each visit, however he blamed the toxins for the twitching and put me on more dialysis, 8 hours on the Cycler, and 12 hours with the gravity bags the ones where you hold it for 4 hours each bag. I now twith uncontrolably even when sitting now, more so when doing the dialysis. I also get very little sleep due to it and find only a sleeping pill does the task of putting me to sleep. There was a time when I went 4 days without dialysis, I was able to sleep very well and easily and the twitching had stopped The only reason I’m on this fage is because I’m doing dialysis now, and as the dialysis fluid flows into me the twiching increases, so much I couldn’t sleep. In fact my legs have been trembling and twiching all through the writting of this message. I believe the Original author of this post as rare as something like this may seem to the trained profeesionals, dosn’t eliminate the possibility that PD dialysis may have such adverse effects on some people. I kmpw I’m starting to get frustrated trying to get my dialysis staff to listen to my serious complaint. It may be cleaning the toxins from mu body, but it’s making me twitch, where I never had a twitch before this cafiter. which seems to be causing another problem I care not dicuss in this forum.I think it not quite right to have suggested a neurologist to Anonymous, as I woudn’t suggest one to you, I just think maybe a more open mind to new possiblities would be more appropriate.