Use of NSAIDs on nocturnal with no kidney function

Thank you for such a quick reply. I had no idea how well these forums were monitored as many threads are somewhat dated.

Residual Kidney Function is a very valid reason for exercising care.

I think a better question may be how dialysis ‘clears’ medications, if, or how well, Hemo/PD work in clearing medications from the system.

I expect depending on molecule size of the med may be a factor in clearance rate. There may also be significant difference clearance rates between the dializer filter used with Hemo vs the body membranes used in PD.

Medication, depending on clearance rates can/may/will need adjustment. This may require study into medications commonly prescribed as to molecule sizes that have not yet been considered/investigated.

Just as we do not want to ‘over’ medicate, we do not want to ‘under’ medicate as well. This can be difficult to determine with the current system of only monthly labs when med changes are ordered.

We still have so much yet to learn.