Hello,
Can you tell me please how exactly diabetes and hypertension lead to chronic kidney disease?
I know that diabetes and hypertension damage the small vessels.
But how exactly they cause kidney failure?
Do they make the glomerular vessels more permeable? Or gradually less permeable due to atherosclerosis or scarring? What exactly damage is responsible for CKD?
Is the Bowman capsule and/or tubules damages? How exactly?
Thanks