Nocturnal Dailey HD vs Nocturnal Dailey HDF? Pros/Cons?

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Hi,

I’m a young adult (23 years of age). A year ago I started dialysis. I’m almost finished with my home training and am keen for nocturnal dialysis however I can’t seem to find much information about the benefits of nocturnal HDF. More specifically I would like to run HDF at a very gentle and slow blood flow rate. Is there a difference between nocturnal HD and HDF? Do I have to run blood flow faster on HDF?

General information on which would be better for me to do would be appreciated. I’m considering doing 6x nocturnal HDF weekly for 8-9 hours.

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Would really love an expert to educate me on this topic!

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Hi PapaS, If you’re in the U.S., there has been limited use of HDF. However, recently Fresenius announced FDA approval of its 2008X machine and dialyzer that can do HDF. I suspect that at least for now this machine will be used for in-center dialysis, but you could contact Fresenius to ask when this treatment will be available for home dialysis. Here’s a press release: Fresenius Medical Care Brings Industry-Leading Dialysis Therapy to Kidney Disease Patients in the U.S., demonstrating Global Leadership in Medical Device and Membrane Engineering Technologies

I’m a social worker and definitely not an expert in this topic. However, there are multiple articles describing hemodiafiltration on the Home Dialysis Central website written by Dr. John Agar, a retired Australian nephrologist. Here are some links:

And there’s this post from a patient with videos and John Agar’s comments in 2020.

I hope this information is helpful.

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