The clinic would need to test your well water for bacterial count, mineral levels, and the presence of chemical residues and such (pesticides, etc.) to see if it can be treated to meet HHD safety standards. That’s the only way to tell. Some folks whose water does not meet those standards use a NxStage machine with bagged fluid, like PD. That may be another option. Rather than consider a treatment, you may want to look at this choice from the perspective of what option would let your life work best. If you haven’t seen our decision aid, My Life, My Dialysis Choice, it can help.